※ 특별강연 강사의 프로필 및 세션 초록을 보기위해서는 제목을 클릭하세요. | 일시: 2023년 11월 11일(토), 연세대학교 치과대학병원 7층 강당 |
등록 및 개회식 사회: 오승한(원광대) | |
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12:30~12:40 | 2023년 대한치과재료학회 추계학술대회 개회사 회장 양형철 |
구두 발표 좌장: 홍민호(강릉원주대) | |
12:40~14:00 | Oral Presentation |
14:00~14:30 | Coffee Break 및 스폰서 온라인 부스 |
포스터 발표 좌장: 안진수(서울대) | |
14:30~15:30 | Poster Presentation |
특별강연 I 좌장: 권일근(경희대) | |
15:30~16:00 | 임형봉 박사(㈜하스) |
“바이오필름 부착 억제효과를 가진 치과용 CAD/CAM 블록과 항우식 생체활성 시멘트의 개발” | |
16:00~16:30 | 박윤정 교수(서울대학교 치의학대학원 구강생화학교실/㈜나이벡) |
“광반응성 펩타이드 융합바이오소재 기반 염증환경제어 조직재생유도 의료기기 상용화” | |
16:30~17:00 | 윤병호 박사(㈜덴티움) |
“자연치 유사 소재 발굴을 통한 틀니용 및 치아모형용 인공치아 개발” | |
특별강연 II 좌장: 권재성(연세대) | |
17:00~17:30 | 최성환 교수(연세대학교 치과대학 교정과학교실) |
“쯔비터를 활용한 방오성 생체활성 재료” | |
시상 및 폐회식 | |
17:30-18:00 | 우수 구연 / 포스터 시상 |
정기총회 | |
18:00~18:30 | 대한치과재료학회 2023년 정기총회 |
특별강연 I-1 좌장: 권일근(경희대) | ![]() |
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특별강연 I-2 좌장: 권일근(경희대) | ![]() |
특별강연 I-3 좌장: 권일근(경희대) | ![]() |
특별강연 II 좌장: 배태성(전북대) | ![]() |
※ Please click session title to have an information about presenter's profile and session abstract. | Date: November 11(Sat) 2023, Auditorium (7th Floor), Yonsei University Dental Hospital |
Registration & Opening Ceremony Moderator: Seunghan Oh (WKU) | |
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12:30~12:40 | Opening Remarks for 2023 Fall Conference of KSDM President: Hyeoong-Cheol Yang (SNU) |
Oral Presentation Chair: Min-Ho Hong (GWNU) | |
12:40~14:00 | Oral Presentation |
14:00~14:30 | Coffee Break & Sponsors’ Online booth |
Poster Presentation Chair: Jin-Soo Ahn (SNU) | |
14:30~15:30 | Poster Presentation |
Special Lecture I Chair : Il-Keun Kwon (KHU) | |
15:30~16:00 | Dr. Hyung-Bong Lim (HASS Co.) |
“Developments of dental CAD/CAM blocks and bioactive cements having an anti-fouling effect to inhibit the biofilm formation” | |
16:00~16:30 | Prof. Yoon-Jung Park (Department of Oral Biochemistry, Seoul National University School of Dentistry/NIBEC Inc.) |
“Photo-reactive Peptide-fusion Biomaterial based Tissue Regenerative Medical Device” | |
16:30~17:00 | Dr. Byung-Ho Yoon (Dentium Co.) |
“Development of artificial teeth for dentures and dental models based on the discovery of natural tooth-like materials” | |
Special Lecture II Chair: Jae-Sung Kwon (YSU) | |
17:00~17:30 | Prof. Sung-Hwan Choi (Department of Orthodontics, College of Dentistry, Yonsei University) |
“Antifouling Bioactive Materials using Zwitterions” | |
Awards Ceremony & Closing Moderator: Seunghan Oh (WKU) | |
17:30-18:00 | Awards Ceremony (Oral & Poster) |
Annual general meeting of the society Moderator: Seunghan Oh (WKU) | |
18:00~18:30 | 2023 Annual general meeting of KSDM |
Dental CAD/CAM blocks embedded antibiotic resistance is so attractive for using in the restorative materials to restore the decayed teeth in terms of oral health. We aim to develop an advanced materials for artificial tooth to inhibit some harmful biofilm formation on restorations or dental cements. The demand for antifouling properties in restorative dentistry has developed various organic-based hybrid materials and bonding agents. While the anti-fouling agents could be deteriorated their mechanical properties that must be considered when they applied in restorative materials.
In this study, we would like to introduce our project strategy to develop the hybrid materials with anti-fouling properties. Dental materials have been focused on developing a little bit resilient materials in line with digital dentistry involving CAD/CAM machining process. The polymer composites filled by functional ceramic particles are a kind of machinable CAD/CAM materials but they are shown a lower mechanical strength (<200 MPa) and deficient abrasion-resistance for the antagonistic tooth than those of pure ceramic restorations. In 2015, the newly invented glass-ceramics with nano-sized lithium disilicate (NLD) were found that Si-rich glass matrix and fine crystalline size could be helpful to improve a chemical bonding strength and mechanical properties with maintain their optical properties.
In conclusion, we try to develop new dental materials by infiltrating monomers with blended antifouling agents into porous NLD glass-ceramics preforms and evaluate their mechanical and biochemical properties to use for dental restoration materials
Unmet needs of current biomaterials in the regenerative practice are lack of bioactivity or control of inflammatory environment. Photoreactive biomaterial that can be cross-linked and stabilized by light to provide the release of incorporated bioactive substance, and at the same time structural stability, would be the ideal alternative or combination of current technology. Our goal of the study has been to develop light-activatable collagen that contain peptide to provide the favorable regenerative environment. The collagen-based biomaterials with the synthetic peptide were combined and the biomaterial was stabilized by the light irradiation. The gel formulation controlled the release of the peptide, and at the same time, the structure was remained during the release. The gel-biomaterial was further evaluated its regenerative potential in the bone defect model and provided significant increased bone formation while reducing inflammatory cells or cytokines. The GLP safety evaluation further confirmed that the photoreactive biomaterial system can be applied to human study.
세계적인 고령화 추세 속에서 임플란트와 의치(틀니)에 대한 수요는 기하급수적으로 증가중으로, 고령자에겐 고가의 임플란트보다는 의치 수요가 더 높으며, 국내도 65세 이상 고령자의 증가로 인해 완전 및 부분 틀니에 대한 수요 또한 급속한 증가가 예상됩니다. 틀니를 구성하는 인공치아/아크릴레진/금속프레임 중에서, 저작활동에 직접 관여하는 인공치아는 1년에 0.006~0.3 mm (Stober, 2020) 정도 마모되며 교체 및 수리가 가장 빈번한 부위입니다. 대합치와 맞닿는 부위에서 교합 안정성을 확보하기 위해서는, 자연치와 마모도가 유사한 내마모성이 가장 이상적입니다. 또한, 2021년부터 국내에서는 치과의사 국가시험에 치아삭제 실기시험을 실시하므로 이를 연습하고 평가하기 위한 치아모형이 필요합니다. 그런데, 틀니용 인공치아 및 치아모형의 경우, 거의 대부분을 수입에 의존하다 보니, 한국인의 구강/치아 특성에 맞지 않는데다 건강보험 재정이 해외로 유출되는 악순환을 겪는 실정입니다. 이를 극복하기 위해, 자연치와 유사한 내마모성을 가지는 틀니용 인공치아와, 치과의사의 훈련/시험에에 맞는 치아모델용 인공치아를 국산화하여, 좋은 제품이 널리 쓰일수 있도록 이바지하고자 합니다.
Oral biofilm consists of more than 700 different types of microorganisms and extracellular polymeric substances (EPS) including exopolysaccharides, proteins, lipids, and nucleic acids. EPS is a multifunctional scaffold that maintains a microenvironment for the growth and reproduction of microorganisms and is also acidic, helping harmful bacteria develop antibiotic resistance. Because of EPS, conventional physical and chemical methods have limitations in removing biofilms once they have matured thickly. Therefore, the prevention of biofilm formation and adhesion at the initial biofilm maturation stage is emerging as a major topic in the development of bioactive materials in dentistry.
In this lecture, I would like to introduce the antifouling effect that prevents bacterial contamination by functionalizing the material surface using zwitterionic polymers (ZP) that are electrically neutral with both positive and negative charges. If a thick hydration shell is formed on the material surface via ZP, it is possible to resist the adhesion of salivary proteins and oral harmful bacteria, and the prevention of enamel demineralization. When multiple ZPs are grafted onto the material surface simultaneously under biological conditions such as saliva, an anti- polyelectrolyte effect occurs accompanied by swelling of the ZP brushes, and hydration enhancement due to weakened inter- and intra-polymer interactions to achieve maximum antifouling effect.
In addition, multiple ZP can act as a multivalent zwitterionic network modifier (α-mZM) for the upregulation of ionic exchange when incorporated with bioactive materials such as glass ionomer cement. Modification with α-mZM elicited the most favorable bioactive response, namely, increased ion elution, in vitro calcium phosphate precipitation, and excellent biofouling resistance, which deterred the growth of the bridging species of Veillonella. Moreover, α-mZM increased early peak expression levels for RUNX2, OCN, and OPN of human dental pulp stem cells in resin-modified glass ionomer cement.
In conclusion, using bioactive materials with zwitterionic polymers, antifouling effects by hydration shell resist pathologic bacterial contamination and normalized microbiome community. Also, due to increasing ion-releasing channels, eluted ions support neutral pH and remineralization potential with human dental pulp stem cell stimulation.